L. plantarum WCFS1 / L. plantarum W1


WCFS1 genomeLactobacillus plantarum W1 (virtually identical to Lactobacillus plantarum WCFS1) is one of the best studied Lactobacilli.


The complete genome of this bacteria has been unraveled. L. plantarum W1 can be grown to high densities, is amenable to genetic transformations and is highly robust with a relatively high survival rate during the gastrointestinal passage.


The excessive amount of research data about L. plantarum W(CFS)1 together with it's fully known genome make this a model bacteria and extremely suitable for a range of probiotic applications. Areas for probiotic application that seem to have potential are; treatment of people with elevated cholesterol levels, indivduals with increased intestinal permeability and diseases where stimulation of TH1 and/or regulatory T cells are benefical.


We have put a great effort in adding this, previous not commercial available, "supreme" bacterium to our collection of bacterial strains. We will now work on how to effectively incorporate this bacterium in our existing and new formulations.


Possible applications are:                          General characteristics:

- Diarrhoea                                                    - QPS (safety) status

- Metabolic syndorme                                  - Human origin

- Ulcerative colitis                                        - Good survival of the GI tract

- Inflammatory bowel disease                  - Good metabolic activity                   

- Cold and flu                                                - Fully known genome

- Autism                                                         - Robust strain

- Gut-brain disorders                                  - Halal     

- General gut health                                    - Allergeen free




Number of scientific publications with Lactobacillus plantarum WCFS1



















 *Number of scientific articles measured on Pubmed May 2013




A selection of publications about L. plantarum W(CFS)1:

Complete genome sequence of Lactobacillus plantarum WCFS1

Complete resequencing and reannotations of the Lactobacillus plantarum WCFS1 genome

Functional analysis of Lactobacillus plantarum WCFS1; a proteomic approach

The proghages sequences of Lactobacillus plantarum strain WCFS1

Effects of administration of Lactobacillus plantarum WCFS1 on small intestinal mucosa